Clinical Trial: A Longitudinal Study of Effect of Copaxone in RRMS Over 24 Months
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: A Prospective, Observational, Single-blinded, Longitudinal MRI Study of Effect of Glatiramer Acetate on Iron Deposition in Patients With Relapsing-remitting Multiple Scler
Brief Summary: To explore whether treatment with glatiramer acetate (GA) may decrease iron deposition in subcortical deep GM, as detected by SWI-filtered phase imaging, in patients with RRMS over 24 months and compared to a reference population of healthy controls.
Detailed Summary: This is a prospective, observational, single-blinded, longitudinal, 24-month MRI study of the evolution of iron deposits, as evidenced by SWI-filtered phase imaging, in RRMS patients treated with GA and in healthy controls.
Sponsor: University at Buffalo
Current Primary Outcome: To explore whether treatment with GA may decrease iron deposition in subcortical deep GM, as detected by SWI-filtered phase imaging, in patients with RRMS over 24 months and compared to a reference population of healthy controls. [ Time Frame: 24 months ]
Original Primary Outcome: Same as current
Current Secondary Outcome: To investigate whether treatment with GA may decrease accumulation of iron in lesions, as detected by SWI-filtered phase imaging, in patients with RRMS over 24 months. [ Time Frame: 24 months ]
Original Secondary Outcome: Same as current
Information By: University at Buffalo
Dates:
Date Received: September 26, 2012
Date Started: June 2012
Date Completion:
Last Updated: March 21, 2013
Last Verified: March 2013