Clinical Trial: Preventing Seroma Formation After Axillary Lymph Node Dissection for Breast Cancer by Early Vacuum Assisted Closure

Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Interventional

Official Title: Preventing Seroma Formation After Axillary Lymph Node Dissection for Breast Cancer by Early Vacuum Assisted Closure--- a Randomized Control Clinical Trial

Brief Summary: Axillary dissection is the standard treatment for breast cancer patients with positive nodes. However, seroma formation after axillary dissection remains the most common early complication to breast cancer surgery. It can delay the initiation of adjuvant therapy, predispose to wound infection, delay wound healing and has also been linked to arm lymphoedema. Based on some studies and our experience that vacuum assisted closure （VAC）is effective in complex wound failures following axillary dissection and groin dissection, we use VAC to prevent seroma formation after extensive axillary dissection. This study is aimed to evaluate the efficacy, safety and economics benefits of early VAC application on postoperative complications and wound healing after extensive axillary dissection in comparison to conventional suction drain.

Detailed Summary:
Sponsor: Changhai Hospital

Current Primary Outcome: seroma formation complication incidence [ Time Frame: within the first 30 days (plus or minus 3 days) after surgery ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Changhai Hospital

Dates:
Date Received: November 19, 2012
Date Started: January 2013
Date Completion: March 2013
Last Updated: November 19, 2012
Last Verified: November 2012