Clinical Trial: The Effect of Dexmedetomidine on Emergence Agitation in Children Undergoing a Surgery Under Desflurane Anesthesia
Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional
Official Title: The Effect of Dexmedetomidine on Emergence Agitation in Children Undergoing a Surgery Under Desflurane Anesthesia
Brief Summary: After genernal anesthesia using sevoflurane or desflurane, the investigators can observe many cases of agiation (over 80%) and despite of no report of long-term complication, agitation is a big issue in PACU for doctors and nurses. The investigators use dexmedetomidine for prevention of agiation of preschool aged children. The investigators expect single injection of dexmedetomidine lead to decrease postoperative agitation and pain without any complication like oculocardiac reflex requiring atopine for treatment.
Detailed Summary: There are four groups accoding to dosage of dexmedetomidine. Dexmedetomidine 0.25 microg.kg(-1),(group D0.25), dexmedetomidine 0.5 microg.kg(-1),(Group D0.5), dexmedetomidine 1 microg.kg(-1) (Group D 1) and normal saline(group P) is administered ivs. for 10mins when we are inducing each patient.
Sponsor: Seoul National University Hospital
Current Primary Outcome: Agitation score [ Time Frame: 30 mins after operation ]
Original Primary Outcome: Same as current
Current Secondary Outcome: Oculomotor reflex [ Time Frame: Intraoperative ]
Original Secondary Outcome: Same as current
Information By: Seoul National University Hospital
Dates:
Date Received: April 13, 2012
Date Started: January 2012
Date Completion: April 2013
Last Updated: April 13, 2012
Last Verified: April 2012