Clinical Trial: Minimal Stimulation or Clomiphene Citrate in Treatment of Polycystic Ovary Syndrome

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Minimal Stimulation or Clomiphene Citrate as First Line Therapy in Women With Polycystic Ovary Syndrome

Brief Summary: The purpose of this study is to compare and determine the the efficacy of minimal stimulation and clomiphene citrate(CC) as the first-line treatment in infertile women with Polycystic Ovary Syndrome(PCOS).

Detailed Summary: All patients received 100 mg CC (Clomid®; Global Napi Pharmaceuticals, Cairo, Egypt) for 5 days starting from day 3 of spontaneous or induced menstruation. In group A (minimal stimulation), 2 vials of highly purified uFSH , 150 IU (Fostimon; IBSA, Lugano, Switzerland, 75 IU/vial) were given IM on cycle day 9. A total of 3 cycles was offered to each group.
Sponsor: Mansoura University

Current Primary Outcome: clinical pregnancy rate per cycle

Original Primary Outcome: Same as current

Current Secondary Outcome: endometrial thickness at the time of hCG administration

Original Secondary Outcome: Same as current

Information By: Mansoura University

Dates:
Date Received: July 6, 2010
Date Started: August 2008
Date Completion:
Last Updated: July 16, 2010
Last Verified: July 2010