Clinical Trial: Biomarkers in Samples From Younger Patients With Wilms Tumor
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Observational - Relationships Between Tumor-Associated Macrophages and Clinicopathological Factors in Wilms Tumor
Brief Summary: This research study is studying biomarkers in tissue samples from younger patients with Wilms tumor. Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. It may also help doctors predict how patients respond to treatment
Detailed Summary:
PRIMARY OBJECTIVES:
I. To determine whether recruitment of tumor-associated macrophages is related to clinicopathological factors in Wilms tumor (tumor stage, presence of vascular invasion, tumor progression, and survival).
OUTLINE:
Paraffin-embedded specimens are analyzed for macrophage markers. Results of each sample are then compared with patient's tumor stage, presence of vascular invasion, tumor progression, and survival.
Sponsor: Children's Oncology Group
Current Primary Outcome: Relationship of tumor-associated macrophages and prognosis [ Time Frame: 1 month ]
Original Primary Outcome: Relationship of tumor-associated macrophages and prognosis
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Children's Oncology Group
Dates:
Date Received: December 15, 2011
Date Started: December 2011
Date Completion:
Last Updated: May 17, 2016
Last Verified: May 2016