Clinical Trial: Physical Activity and Cognitive Behavioural Therapy in Panic Disorder

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: The Influence of Physical Activity on the Effect of Cognitive Behavioural Therapy, Neurobiological Parameters and Information Processing in Patients With Panic Disorder Wi

Brief Summary: Physical activity (treadmill) supports the effect of cognitive behavioural therapy in patients with panic disorder with/without agoraphobia

Detailed Summary:

Patients undergo cognitive behavioural therapy consisting of 8 group sessions within 1 month. All patients additionally complete a training of physical activity, which starts simultaneously to therapy and runs for 8 weeks (3 times/week, 30 minutes each). Half of the patients complete training on a treadmill while the other half completes a training programme of low intensity physical activity without cardiovascular activation.

Flanking EEG (electroencephalogram) recordings shall help clarify biological processes underlying the therapeutical process.


Sponsor: Charite University, Berlin, Germany

Current Primary Outcome: Hamilton Rating Scale for Anxiety (CIPS 1995) [ Time Frame: up to 28 weeks (follow up) ]

Global interviewer rated measure for anxiety and severity indicator of an anxiety disorder


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Panic and Agoraphobia Scale (Bandelow et al. 1995) [ Time Frame: Baseline, 4 weeks, 8 weeks and 28 weeks (follow up) ]
  • Beck Anxiety Inventory (CIPS 1995) [ Time Frame: Baseline, 4 weeks, 8 weeks and 28 weeks (follow up) ]
  • Clinical Global Index (CIPS 1995) [ Time Frame: Baseline, 4 weeks, 8 weeks and 28 weeks (follow up) ]
  • Beck Depression Inventory (CIPS 1995) [ Time Frame: Baseline, 4 weeks, 8 weeks and 28 weeks (follow up) ]


Original Secondary Outcome: Same as current

Information By: Charite University, Berlin, Germany

Dates:
Date Received: February 4, 2013
Date Started: January 2009
Date Completion:
Last Updated: May 15, 2013
Last Verified: May 2013