Clinical Trial: Treatment of Orthostatic Intolerance

Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Interventional

Official Title: Treatment of Orthostatic Intolerance

Brief Summary: This trial is designed to study the effects of various mechanistically unique medications in controlling excessive increases in heart rate with standing and in improving the symptoms of orthostatic intolerance in patients with this disorder.

Detailed Summary:
Sponsor: Satish R. Raj

Current Primary Outcome: Increase in heart rate with standing [ Time Frame: 1-4 hours ]

Original Primary Outcome: Increase in heart rate with standing

Current Secondary Outcome:

  • Sitting heart rate [ Time Frame: 1-4 hours ]
  • Standing heart rate [ Time Frame: 1-4 hours ]
  • Blood pressure [ Time Frame: 1-4 hours ]
  • Decrease in blood pressure with standing [ Time Frame: 1-4 hours ]
  • Orthostatic symptoms score [ Time Frame: Baseline, 2h, 4h ]


Original Secondary Outcome:

  • Sitting heart rate
  • Standing heart rate
  • Blood pressure
  • Decrease in blood pressure with standing
  • Orthostatic symptoms score


Information By: Vanderbilt University

Dates:
Date Received: December 5, 2005
Date Started: April 1997
Date Completion:
Last Updated: August 15, 2016
Last Verified: August 2016