Clinical Trial: The Effect of Oral β- Glucan Supplement on Appetite and Insulin Resistance in Non Alcoholic Fatty Liver Disease

Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional

Official Title: The Effect of Oral β- Glucan Supplement on Anthropometric Measurements, Appetite, Insulin Resistance, Liver Echogenicity and Enzymes in Non Alcoholic Fatty Liver Disease

Brief Summary: The Objective of This Study is Evaluating the Effect of oral β- glucan Supplement on Anthropometric Measurements, Appetite, Insulin Resistance, Liver echogenicity and Enzymes in Non Alcoholic Fatty Liver Patients Treating with Hypocaloric Diet and Vitamin E.

Detailed Summary:
Sponsor: Urmia University of Medical Sciences

Current Primary Outcome:

  • Liver Echogenicity [ Time Frame: 8 weeks ]
    Liver Echogenicity Describes by Grade,
  • Liver Enzymes [ Time Frame: 8 weeks ]
    Enzymes ALP (Alkanin Phosphatase), ALT (Alanin Amino Transferase) and AST (Aspartat Amino Transferase)


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Anthropometric Measurement WHtR [ Time Frame: 4 weeks, 8 weeks ]
    WHtR (waist to Height ratio)
  • Appetite [ Time Frame: 4 weeks, 8 weeks ]
    NAS (numeric Analuge Scale) cm
  • Insulin Resistance [ Time Frame: 8 weeeks ]
    Describe by HOMA-IR (Homeostasis Model Assessment of Insulin Resistance)
  • Anthropometric Measurement WC [ Time Frame: 4weeks, 8 weeks ]
    WC (waist circumference) measures by "cm"
  • Anthropometric Measurement WHR [ Time Frame: 4 weeks, 8 weeks ]
    WHR (waist to hip ratio)
  • Anthropometric Measurement BMI [ Time Frame: 4 weeks, 8 weeks ]
    BMI (Body Mass Index) kg/m2
  • Peptide YY (PYY) Hormone [ Time Frame: 8 weeks ]
    Elayza kit
  • Cholecystokinin (CKK) Hormone [ Time Frame: 8 weeks ]
    Elayza kit
  • Fasting Blood Sugar [ Time Frame: 8 weeks ]
    FBS (Fasting Blood Sugar) mmol/lit


Original Secondary Outcome: Same as current

Information By: Urmia University of Medical Sciences

Dates:
Date Received: June 18, 2014
Date Started: July 2014
Date Completion:
Last Updated: June 27, 2014
Last Verified: June 2014