Clinical Trial: EFECAB: Improving Pig Management to Prevent Epilepsy in Burkina Faso

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: EFECAB: Improving Pig Management to Prevent Epilepsy in Burkina Faso

Brief Summary: This is a pre-post randomized community-based controlled trial aimed at estimating the effectiveness of an educational package developed using PRECEDE PROCEED to reduce the cumulative incidence of Taenia solium cysticercosis in three Provinces of Burkina Faso. The study design included an 18-months baseline study to measure baseline cumulative incidence of cysticercosis followed by an 18-month post randomization study to measure the effectiveness of the intervention. Sixty villages of three Provinces of Burkina Faso were included. The primary outcome was the change in the baseline to post randomization cumulative incidence in the intervention group compared to the control group.

Detailed Summary:
Sponsor: University of Oklahoma

Current Primary Outcome: Human active cysticercosis cumulative incidence [ Time Frame: baseline, 18 months follow-up pre randomization, 18 months follow-up post randomization ]

Sero conversion to the AgELISA test to detect antigens of cysticercosis


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Porcine active cysticercosis prevalence [ Time Frame: baseline, 18 months follow-up pre randomization, 18 months follow-up post randomization ]
    Sero-positivity to the AgELISA test to detect antigens of cysticercosis
  • Change in knowledge, attitude and practices [ Time Frame: baseline, 18 months follow-up pre randomization, 18 months follow-up post randomization ]
    Change in answers to the questionnaire through time
  • Cumulative incidence of epilepsy and progressively worsening severe chronic headaches [ Time Frame: baseline, 18 months follow-up pre randomization, 18 months follow-up post randomization ]
    development of neurological disorders among those followed up at least twice
  • Stigmatization of epilepsy [ Time Frame: 18 months follow-up post randomization ]
    Attitudes and knowledge regarding epilepsy post randomization


Original Secondary Outcome: Same as current

Information By: University of Oklahoma

Dates:
Date Received: March 22, 2017
Date Started: February 21, 2011
Date Completion:
Last Updated: March 22, 2017
Last Verified: March 2017