Clinical Trial: Study of tDCS for Mild Cognitive Impairment

Study Status: Active, not recruiting
Recruit Status: Unknown status
Study Type: Interventional

Official Title: A Study for the Short- and Long-term Improvement of Cognitive Function (Evaluated by PET-CT and SNSB) After Transcranial Direct Current Stimulation in Mild Cognitive Impairment

Brief Summary: The primary objective of this study is to investigate whether the transcranial direct current stimulation (tDCS) improves the cognitive function in patients with Mild Cognitive Impairment (MCI)

Detailed Summary: Twenty-four patients were recruited and randomized to receive either real- or sham-tDCS over the left (anode) and right (cathode) dorsolateral prefrontal cortex (DLPFC). Their legally responsible caregivers were provided with mobile tDCS device, and were instructed to use it on the patients at the hospital. 30-minute session of the stimulation were applied 3 times a week for 12 weeks. The patients were evaluated at baseline and at Week 12.
Sponsor: Incheon St.Mary's Hospital

Current Primary Outcome: Change in PET-CT images [ Time Frame: from baseline to Week 12 ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

• Change in Cognitive function [ Time Frame: from baseline to Week 12 ]
  Measured by SNSB
• Change in Cognitive function [ Time Frame: from baseline to Week 12 ]
  Measured by Korean version of Mini Mental Status Examination (K-MMSE) and Clinical Dementia Rating (CDR)
• Change in activities of daily living [ Time Frame: from baseline to Week 12 ]
  Measured by B-ADL
• Change in Geriatric Depression Scale [ Time Frame: from baseline to Week 12 ]

Original Secondary Outcome: Same as current

Information By: Incheon St.Mary's Hospital

Dates:
Date Received: December 16, 2014
Date Started: December 2014
Date Completion: April 2015
Last Updated: December 16, 2014
Last Verified: December 2014