Clinical Trial: Eradication of Helicobacter Pylori in the Management of Stage IE & IIE-1 Primary Low-grade B Cell Lymphoma of MALToma
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Eradication of Helicobacter Pylori in the Management of Stage IE & IIE-1 Primary Low-grade B Cell Lymphoma of Mucosa-associated Lymphoid Tissue Type of The Stomach
Brief Summary: To evaluate the therapeutic effectiveness of H. pylori eradication in stage IE & IIE-1 primary low-grade B cell lymphoma of MALT of the stomach
Detailed Summary:
To investigate the prevalence of H. pylori infection in patients with early stage of primary low-grade B cell lymphoma of MALT of the stomach in Taiwan.
-To evaluate the therapeutic effectiveness of H. pylori eradication in stage IE & IIE-1 primary low-grade B cell lymphoma of MALT of the stomach.
To evaluate the efficacy of Helicobacter pylori eradication therapy with respect to objective regression rate and time to disease progression of primary low-grade gastric MALToma.
To estimate any differences in therapeutic efficacy related to different stage of disease,eg. stage IE v.s. stage IIE-1.
To identify the causes of treatment failure, such as the stage of tumor, the presence of large cell component, and/or persistent, reactivation or reinfection of H. pylori etc.
Sponsor: National Health Research Institutes, Taiwan
Current Primary Outcome: evaluate the efficacy of Helicobacter pylori eradication therapy with respect to objective regression rate and time to disease progression of primary low-grade gastric MALToma. [ Time Frame: Four weeks after the completion of anti-H. pylori therapy by CT scan ]
Original Primary Outcome: therapeutic effectiveness
Current Secondary Outcome: objective regression rate and time to disease progression of primary low-grade gastric MALToma. [ Time Frame: 3-6 months by EUS ]
Original Secondary Outcome: objective regression rate and time to disease progression of primary low-grade gastric MALToma.
Information By: National Health Research Institutes, Taiwan
Dates:
Date Received: September 13, 2005
Date Started: June 1996
Date Completion:
Last Updated: March 25, 2016
Last Verified: March 2016