Clinical Trial: Assessment of Postoperative Lymphopenia as Risk Factor for Postoperative Infections
Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Observational
Official Title: Assessment of Postoperative Lymphopenia as Risk Factor for Postoperative Infections: EVALYMPH Study
Brief Summary: Postoperative infections are one of the most common complications in thoracic and digestive cancer surgery. Former studies have demonstrated that inflammatory response is altered during peri-operative period causing lymphopenia. It has been suggested that lymphopenia may contribute to postoperative infection. To date, no one has proved it in a multivariate analysis. The aim of this study is to determine if lymphopenia is associated with postoperative infections in thoracic and digestive cancer surgery.
Detailed Summary:
Postoperative infections are one of the most common complications in thoracic and digestive cancer surgery. Former studies have demonstrated that inflammatory response is altered during peri-operative period causing lymphopenia. It has been suggested that lymphopenia may contribute to postoperative infection. To date, no one has proved it in a multivariate analysis.
The aim of this study is to determine if lymphopenia is associated with postoperative infections in thoracic and digestive cancer surgery. It is a multicenter French cohort study. Lymphocytes counts are obtained from patients undergoing pulmonary or digestive cancer surgery before surgery (day-0) as well 1, 3, 5 and 8 days after surgery. Anesthetic and surgical procedures are collected as well as risk factors for postoperative infections recognized in the literature. Clinical and biological signs of infection are collected.
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Current Primary Outcome: Presence of post operative infection [ Time Frame: 1 month ]
Original Primary Outcome: Same as current
Current Secondary Outcome: Anesthetic and surgical parameters [ Time Frame: 1 month ]
Original Secondary Outcome: Same as current
Information By: Centre Hospitalier Universitaire de Saint Etienne
Dates:
Date Received: June 10, 2016
Date Started: June 2016
Date Completion: July 2017
Last Updated: June 13, 2016
Last Verified: June 2016