Clinical Trial: Granulocyte Colony Stimulating Factor (G-CSF) in Acute Liver Failure and Alcoholic Hepatitis

Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Interventional

Official Title: G-CSF in Acute Liver Failure and Alcoholic Hepatitis - A Pilot Study

Brief Summary: Granulocyte colony stimulating factor in acute liver failure and alcoholic hepatitis

Detailed Summary: In this study 4 groups have been taken. Two groups of cases including Alcoholic patients and acute liver failure which are given G-CSF therapy and two groups of controls given standard therapy. Primary end point is to see the mobilization of CD-34 hematopoietic cells and survival. Secondary end point is to see the clinical and biochemical improvement in liver functions.
Sponsor: Postgraduate Institute of Medical Education and Research

Current Primary Outcome: • Mobilization of CD34 cells in the peripheral blood, a surrogate marker for hematopoietic stem cell mobilization [ Time Frame: 1 year ]

Original Primary Outcome: Same as current

Current Secondary Outcome: clinical and biochemical improvement in liver functions [ Time Frame: 1 year ]

Original Secondary Outcome: Same as current

Information By: Postgraduate Institute of Medical Education and Research

Dates:
Date Received: April 15, 2011
Date Started: June 2010
Date Completion: June 2011
Last Updated: April 25, 2011
Last Verified: January 2011