Clinical Trial: Clinical Impacts of Oral Gastrografin Follow Through in Adhesive Small Bowel Obstruction (SBO)

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Clinical Impacts of Oral Gastrografin Follow Through in Adhesive Small Bowel Obstruction (SBO).

Brief Summary:

Mini abstract :

Altogether 100 patients with 117 episodes of ASBO were randomized into control and gastrografin groups. Eight episodes in eight patients were excluded. Gastrografin group showed a significant decrease of both the time between admission and operation and that of hospital stay .The need for surgery was reduced but statistically insignificant.

Detailed Summary:

Abstract

Background:

Many published studies have shown that Gastrografin can be used for diagnosis post operative acute small bowel obstruction (ASBO) and assessing the need for surgical intervention .However,the studies have reported conflicting results hence the aim of our study to test this hypothesis.

Patients and methods :

Altogether 100 patients with 117 episodes of ASBO were randomized into control and gastrografin groups in a double blinded fashion. Eight episodes in eight patients were excluded due to protocol violation. In Gastrografin group,100 ml of the dye administered through a nasogastric tube and complete obstruction has been considered if the contrast failed to reach the colon on the 24-hour film. Patients were operated on only if they developed signs of strangulation or failed to improve within 48 hours.

Sponsor: Mansoura University

Current Primary Outcome: resolving [ Time Frame: 48 hours ]

Original Primary Outcome: Same as current

Current Secondary Outcome: non resolving [ Time Frame: 48 hours ]

Original Secondary Outcome: Same as current

Information By: Mansoura University

Dates:
Date Received: August 19, 2008
Date Started: February 2006
Date Completion:
Last Updated: November 25, 2008
Last Verified: August 2008