Clinical Trial: Effects of L-carnitine on Hypothyroidism
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Single-center, Randomized, Double-Blinded, Comparative Study of the Effectiveness of L-carnitine in Patients'Fatigue Degree Changing With Hypothyroidism Who Take Levothyro
Brief Summary: L-carnitine and thyroid hormone tended to antagonize reciprocally in human body. Urinary excretion of L-carnitine decreased in hypothyroid patients, and levothyroxine supplementation increased excretion of L-carnitine. The investigators hypothesized that supplying L-carnitine to hypothyroid patients with fatigue symptom could improve the quality of life, and fatigue score in them. Therefore, the investigators planned to compare the efficacy of L-carnitine and placebo in hypothyroid patients who had taken levothyroxine.
Detailed Summary:
Sponsor: Korea University Anam Hospital
Current Primary Outcome: Fatigue Severity scale [ Time Frame: baseline and 12 weeks ]
Original Primary Outcome: Same as current
Current Secondary Outcome: Wessely and Powell score [ Time Frame: baseline and 12 weeks ]
Original Secondary Outcome: Same as current
Information By: Korea University Anam Hospital
Dates:
Date Received: January 10, 2013
Date Started: August 2012
Date Completion:
Last Updated: December 2, 2013
Last Verified: December 2013