Clinical Trial: Bioimpedance Spectroscopy for the Differential Diagnosis of Hyponatremia
Study Status: Completed
Recruit Status: Completed
Study Type: Observational [Patient Registry]
Official Title: Bioimpedance Spectroscopy for the Differential Diagnosis of Hyponatremia
Brief Summary: We aimed to investigate the role of bioimpedance spectroscopy for the diagnosis of hyponatremia
Detailed Summary:
- Up to now, "Hyponatremia" differentially diagnosed by physical examination, plasma and urine osmolalities, Echocardiography and biochemical measurements.
- The purpose of this study is to determine whether bioimpedance spectroscopy can be used for the detection of hypovolemia and hypervolemia for the differential diagnosis of hyponatremia.
Sponsor: Zonguldak Karaelmas University
Current Primary Outcome: Accuracy of volume status measured by bioimpedance spectroscopy [ Time Frame: Six months ]
BIOIMPEDANCE SPECTROSCOPY:
Overhydration (OH) measurement by Body Composition Monitor (Fresenius Medical Care)
Negative values of "OH" indicating Hypovolemia and positive values for hypervolemia in hyponatremic patients.
Original Primary Outcome: Same as current
Current Secondary Outcome: Laboratory data and echocardiography [ Time Frame: 6 Months ]
LABORATORY MEASUREMENTS Hemoglobin, Hematocrit, White blood cell count Platelet count, Na, Potassium, Chlorur, Urea, Creatinine, Uric acid, Plasma osmolality, Urine osmolality, Alanine transaminase , Aspartate transaminase , Urine specific gravity,
TREATMENT MODALITY
- Diuretics
- Intravenous hydration by isotonic saline
ECHOCARDIOGRAPHY:
Left ventricular end-diastolic diameter, Left ventricular end-systolic diameter, Ejection fraction(%), Left Atrium diameter, Aortic diameter, Right atrium diameter, Interventricular septum, Posterior wall thickness, Mitral insufficiency, Pulmonary insufficiency, Systolic pulmonary artery pressure, Tricuspid insufficiency
Original Secondary Outcome: Same as current
Information By: Zonguldak Karaelmas University
Dates:
Date Received: April 20, 2013
Date Started: February 2013
Date Completion:
Last Updated: October 30, 2014
Last Verified: October 2014