Clinical Trial: Effects of Lovaza on High Density Lipoprotein (HDL) Composition and Function in Hypertriglyceridemia
Study Status: Withdrawn
Recruit Status: Withdrawn
Study Type: Interventional
Official Title: Effects of Lovaza Monotherapy vs. Placebo on Composition and Function of HDL and Other Lipoproteins, and on Other Lipid-Related Parameters
Brief Summary:
Study hypothesis: Lovaza (purified prescription fish oil) is likely to help HDL (the "good cholesterol") work better.
Study summary: We are testing effects of Lovaza versus placebo, on various aspects of HDL and other lipoproteins, in patients with high triglyceride levels.
Study funding: This study is being funded by an investigator-initiated research grant from Glaxo Smith Kline.
Detailed Summary:
Sponsor: University of Utah
Current Primary Outcome: HDL Composition [ Time Frame: 12 weeks ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- HDL cholesterol composition by density subfraction [ Time Frame: 12 weeks ]HDL composition by density gradient ultracentrifugation
- Safety [ Time Frame: 12 weeks ]Transaminases and glucose levels
Original Secondary Outcome: Same as current
Information By: University of Utah
Dates:
Date Received: May 17, 2010
Date Started: August 2010
Date Completion: October 2012
Last Updated: February 4, 2016
Last Verified: July 2011