Clinical Trial: Evaluation of Oxidative Stress and Effect of Levothyroxine Treatment on Oxidative Stress in Hashimoto Disease
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Evaluation of Oxidative Stress and Effect of Levothyroxine Treatment on Oxidative Stress in Hashimoto Disease
Brief Summary: Oxidative stress leads to or accompanies with numerous disease. Oxidative balance in subclinical hypothyroid or euthyroid state in Hashimoto disease are not known. Effect of levothyroxine therapy on oxidative balance are also not known in hashimoto disease.
Detailed Summary: oxidative stress markers will be measured initially(TAS,TOS,OSI,PARAOXONASE,ARYLESTERASA,PON1 PHENOTYPİNG,LİPİDPEROXİD).After 3 months therapy with levothyroxine measurements will be repeated except PON1 phenotyping.
Sponsor: Vakif Gureba Training and Research Hospital
Current Primary Outcome: Poxidative stress markers [ Time Frame: After levotren therapy ]
Original Primary Outcome:
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Vakif Gureba Training and Research Hospital
Dates:
Date Received: April 9, 2010
Date Started: April 2010
Date Completion:
Last Updated: June 11, 2013
Last Verified: June 2013