Clinical Trial: Energy Expenditure of People Living With HIV/AIDS
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Influence of Lipid-lowering Drugs in Patients Seropositive for HIV With Lipodystrophy in Resting Energy Expenditure and Total Energy Expenditure
Brief Summary:
Background: Several studies have reported increased resting energy expenditure (REE) in people living with HIV/AIDS possibly due to changes in body composition that occurs in HIV lipodystrophy syndrome.
The aim of this study was to evaluate the influence of the use of lipid-lowering drugs in resting energy expenditure (REE) and total energy expenditure (TEE) in patients seropositive for HIV in treatment of lipodystrophy.
Detailed Summary:
REE was measured by indirect calorimetry.
TEE was measured by doubly labeled water (DLW) technique and an activity monitor based on accelerometry (AM).
Sponsor: University of Sao Paulo General Hospital
Current Primary Outcome:
- Total Energy Expenditure (kcal/d) [ Time Frame: 14 day ]
- Resting Energy Expenditure (kcal/d) [ Time Frame: 1 day ]
Original Primary Outcome: Same as current
Current Secondary Outcome: Correlation between doubly labeled water and accelerometer to measure total energy expenditure (ICC, 95% CI) [ Time Frame: 14 days ]
Original Secondary Outcome: Same as current
Information By: University of Sao Paulo General Hospital
Dates:
Date Received: August 4, 2015
Date Started: March 2013
Date Completion:
Last Updated: August 20, 2015
Last Verified: August 2015
