Clinical Trial: Treatment of Soft Tissue Expansion in Inactive Thyroid Eye Disease Patients Using Drops of Prostaglandin Analogues
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Phase 3 Study of Treatment of Soft Tissue Expansion and Exophthalmos in Inactive Thyroid Eye Disease Patients Using Drops of Prostaglandin Analogues.
Brief Summary: Prostaglandin analogues eye drops are common and effective treatment for decreasing Intra-Ocular Pressure (IOP) in Glaucoma patients. A number of recently published case reports have documented periorbital fat atrophy following treatment by prostaglandin analogues. In this study the investigators want to use this side-effect of prostaglandin analogues for the treatment of orbital and periocular fat proliferation in inactive Thyroid eye disease (TED) patients, as a conservative substitute for surgical intervention.
Detailed Summary:
Sponsor: Rabin Medical Center
Current Primary Outcome: Bimatoprost effect on soft tissue amount and exophthalmos in inactive TED patients. [ Time Frame: 6 months ]
Original Primary Outcome: Same as current
Current Secondary Outcome: Number of participants with adverse events. [ Time Frame: 9 months ]
Original Secondary Outcome: Same as current
Information By: Rabin Medical Center
Dates:
Date Received: May 21, 2014
Date Started: November 2014
Date Completion:
Last Updated: June 14, 2015
Last Verified: June 2015