Clinical Trial: The Effectiveness of Neuropsychological Rehabilitation in Young Dyslexic Adults

Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Interventional

Official Title: The Effectiveness of Neuropsychological Rehabilitation in Young Dyslexic Adults - a Single Blind, Randomized, Controlled Study

Brief Summary: The purpose of this study is to determine whether individual and/ group based neuropsychological rehabilitation focused on psychoeducation and teaching compensatory strategies has positive effects on the psychosocial wellbeing and perceived cognitive deficits in dyslexic young adults. The hypothesis is that both individual and group based neuropsychological rehabilitation show positive effects on the psychosocial wellbeing and perceived cognitive deficits. Another purpose of this study is to evaluate weather individual and group based neuropsychological rehabilitation have different kind of effects on the wellbeing of the participants and weather either one of the rehabilitation formats is more effective than the other.

Detailed Summary:

Background: Untreated dyslexia causes problems for individuals in studies, work and employment. High quality research on the best and most cost-effective rehabilitation methods is needed.

Objective: To study whether neuropsychological rehabilitation improves the psychosocial wellbeing and perceived cognitive deficits in dyslexic young adults and to evaluate potential differences between individual and group based neuropsychological rehabilitation.

Methods: Altogether 120 young adults diagnosed with dyslexia are randomized either to one of the intervention groups (individual neuropsychological rehabilitation / group neuropsychological rehabilitation) or to a control group which will receive either one of the interventions after a 5 month waiting period. All the study subjects are assessed with a short neuropsychological test battery as well as self-rating questionnaires evaluating mood, QoL, perceived cognitive deficits, and the impact of the learning disability at baseline, after five months (immediately after interventions or control period) and after 10 months. After 20 months a shorter follow-up using only self-ratings will be done via mail. Subjects in the intervention groups are offered neuropsychological rehabilitation in 12 sessions conducted once a week or once in two weeks during five months. Subjects in the control group do not receive any intervention for the first five months.

Results: The effects of interventions on psychosocial wellbeing and perceived cognitive deficits are evaluated using appropriate statistical procedures and comparing the differences between the interventions groups and the control group.

The present status: All the interventions are completed, follow-up data is still beeing collected

Sponsor: Rehabilitation Foundation, Finland

Current Primary Outcome:

• Subjective cognitive performance [ Time Frame: 5 months ]
  The effects of rehabilitation on subjective cognitive performance: Everyday Memory Questionnaire (EMQ)
• Subjective reading related performance [ Time Frame: 5 months ]
  Effects of rehabilitation on subjective reading related performance: Adult Reading History Questionnaire (ARHQ) modified

Original Primary Outcome: Same as current

Current Secondary Outcome:

• Objective cognitive performance [ Time Frame: 5 months ]
  Effects of rehabilitation on objective cognitive performance: a neuropsychological test battery (verbal and design fluency, SDMT, WAIS-IV Digit span, WMS-III Word list, V3/AVO-9, WMS-III Logical Memory I, WMS-III Visual Reproduction, TM-a, TM-b, RAS)
• Goal achievement [ Time Frame: 5 months ]
  Goal achievement: Goal Attainment Scaling (GAS)
• Quality of life [ Time Frame: 5 months ]
  The effects of rehabilitation on QoL: QOLIBRI bref.
• Mood [ Time Frame: 5 months ]
  The effects of rehabilitation on mood: Profile of Mood States (POMS)
• Social and cognitive behavioral strategies [ Time Frame: 5 months ]
  Strategy and Attribution Questionnaire (SAQ) bref

Original Secondary Outcome: Same as current

Information By: Rehabilitation Foundation, Finland

Dates:
Date Received: August 14, 2013
Date Started: November 2012
Date Completion: December 2017
Last Updated: January 20, 2017
Last Verified: April 2016