Clinical Trial: Adverse Drug Reactions With Fatal Outcome
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Adverse Drug Reactions With Fatal Outcome
Brief Summary: The purpose of this study is to determine the incidence of drug-related deaths in a university hospital during the year 2015
Detailed Summary: The investigators aimed to determine the incidence of drug-related mortality of admitted patients in a university hospital during the year 2015
Sponsor: Germans Trias i Pujol Hospital
Current Primary Outcome: Incidence of drug-related deaths of all hospital admissions [ Time Frame: during the year 2015 ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Number of drug-related deaths with the suspected drug started the previous week [ Time Frame: during the year 2015 ]
- Number of drug-related deaths with drug interactions between suspected drugs [ Time Frame: during the year 2015 ]
- Number of preventable drug-related deaths assessed by Schumock criteria [ Time Frame: during the year 2015 ]
- Number of drug-related deaths with polypharmacy [ Time Frame: during the year 2015 ]Polypharmacy: when patient received >10 drugs
- Number of drug-related deaths with autopsy [ Time Frame: during the year 2015 ]
- Number of drug-related deaths in which the suspected drug had a contributive role [ Time Frame: during the year 2015 ]
- Number of drug-related deaths with "certain" or "probable" categories assessed by World Health Organization (WHO) criteria and Naranjo algorithm [ Time Frame: during the year 2015 ]
- Number of drug-related deaths presented during hospitalization [ Time Frame: during the year 2015 ]
- Risk factors of drug-related deaths [ Time Frame: during the year 2015 ]risk factors assessed: age, sex, Charlson score, and hospitalization length
- Incidence of drug-related deaths of all inpatients deaths [ Time Frame: during the year 2015. ]
Original Secondary Outcome: Same as current
Information By: Germans Trias i Pujol Hospital
Dates:
Date Received: July 13, 2016
Date Started: February 2016
Date Completion:
Last Updated: July 15, 2016
Last Verified: July 2016