Clinical Trial: A Predictive Score for the Ischemic Etiology of a Transient Diplopia (VASCO-DIP)

Study Status: Enrolling by invitation
Recruit Status: Enrolling by invitation
Study Type: Observational

Official Title: Development and Validation of a Predictive Score for the Ischemic Etiology of a Transient Diplopia

Brief Summary:

The transient diplopias (TD) is defined by a short diplopia. Their etiology may be ophthalmological, neurological non-ischemic or of ischemic origin.

The difficulty is to recognize an ischemic mechanism which imposes emergency cares.

A clinical score could help the clinician to recognize the etiology of the TD .


Detailed Summary:
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild

Current Primary Outcome: Etiology, ischemic or not, of the initial transient diplopia [ Time Frame: 3 months ]

Questionnaire about the symptoms and about the vascular risk factors, cerebral MRI, MRI angiography of the supra-aortic trunks, ECG, Holter, transthoracic echocardiography, blood count, erythrocytes sedimentation rate, C reactive protein, visual field, optical coherence tomography, retinography and a new evaluation after 3 months.


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Incidence of new transient diplopia ischemic attacks during the 3 months of follow-up [ Time Frame: 3 months ]
    Questionnaire about the symptoms and about the vascular risk factors, cerebral MRI, MRI angiography of the supra-aortic trunks, ECG, Holter, transthoracic echocardiography, blood count, erythrocytes sedimentation rate, C reactive protein, visual field, optical coherence tomography, retinography and a new evaluation after 3 months.
  • Incidence of diplopia ischemic strokes during the 3 months of follow-up [ Time Frame: 3 months ]
    Questionnaire about the symptoms and about the vascular risk factors, cerebral MRI, MRI angiography of the supra-aortic trunks, ECG, Holter, transthoracic echocardiography, blood count, erythrocytes sedimentation rate, C reactive protein, visual field, optical coherence tomography, retinography and a new evaluation after 3 months.
  • Incidence of transient ischemic attacks, visual or not visual, during the 3 months of follow-up [ Time Frame: 3 months ]
    Questionnaire about the symptoms and about the vascular risk factors, cerebral MRI, MRI angiography of the supra-aortic trunks, ECG, Holter, transthoracic echocardiography, blood count, erythrocytes sedimentation rate, C reactive protein, visual field, optical coherence tomography, retinography and a new evaluation after 3 months.
  • Incidence of ischemic strokes, visual or not visual, during the 3 months of follow-up [ Time Frame: 3 months ]
    Questionnaire about the symptoms and about the vascular risk factors, cerebral MRI, MRI angiography of the supra-aortic trunks, ECG, Holter, transthoracic echocardiography, blood count, erythrocytes sedimentation rate, C reactive protein, visual field, optical coherence tomography, retinography and a new evaluation after 3 months.


Original Secondary Outcome: Same as current

Information By: Fondation Ophtalmologique Adolphe de Rothschild

Dates:
Date Received: October 13, 2015
Date Started: September 2015
Date Completion: April 2019
Last Updated: February 3, 2017
Last Verified: February 2017