Clinical Trial: Pathogenic Species and Genotypes of Bacterial Diversity in Relation to the Severity of Dental Caries
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational
Official Title: Prevalence and Identification of Pathogenic Species and Genotypes of Bacterial Diversity in Relation to the Severity of Dental Caries
Brief Summary: The primary objective of this study is to estimate the distribution of pathogenic species and genotypes of bacterial diversity in 7 stages ICDAS (International Caries Detection and Assessment System) corresponding to the severity of dental caries among patients aged 3-45 years consulting in the Dentistry Departments of the Nîmes University Hospital and the Montpellier University Hospital.
Detailed Summary:
Secondary objectives include:
- Compare the distribution of bacterial species in relation to stages of severity of caries
- Compare the results from plaque with those of saliva samples.
Sponsor: Centre Hospitalier Universitaire de Nīmes
Current Primary Outcome:
- Bacterial profile [ Time Frame: Baseline (day 0) ]Bacterial profiles will be constructed using saliva and plaque samples.
- ICDAS assessment [ Time Frame: Baseline (day 0) ]Dental caries will be assessed using the ICDAS (International Caries Detection and Assessment System) system
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Studies were stopped during high school? yes/no [ Time Frame: baseline (Day 0) ]
- Does the patient have at least five fillings? yes/no [ Time Frame: Baseline (day 0) ]
- Does the patient have at least one filling and one missing tooth on the anterior sector following the carious lesion? yes/no [ Time Frame: baseline (day 0) ]
- Within the last 12 months, the patient has had dental care or tooth removal following the carious lesion? yes/no [ Time Frame: baseline (day 0) ]
- Yesterday, did the patient eat at least three snacks (or sugary or carbonated drinks) between meals? yes/no [ Time Frame: Baseline (day 0) ]
- Yesterday, did the patient brush his/her teeth fewer than 2 times? yes/no [ Time Frame: baseline (day 0) ]
- The patient has at least one carious lesion restricted to the enamel? yes/no [ Time Frame: baseline (day 0) ]
- The patient has at least one carious lesion restricted to the enamel on an anterior tooth or involving the smooth surface on a posterior tooth (yes/no) [ Time Frame: baseline (day 0) ]
- The patient has at least one carious lesion attacking the dentin or pulp. yes/no [ Time Frame: baseline (day 0) ]
- The patient has at least one carious lesion reaching dentin or pulp on an anterior tooth or on the smooth surface of a posterior tooth (yes/no) [ Time Frame: baseline (day 0) ]
Original Secondary Outcome: Same as current
Information By: Centre Hospitalier Universitaire de Nīmes
Dates:
Date Received: February 4, 2014
Date Started: March 15, 2016
Date Completion: March 2017
Last Updated: January 31, 2017
Last Verified: March 2016