Clinical Trial: Biotin Status in Pregnancy
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Biotin Status in Pregnancy
Brief Summary: The purpose of this study is to estimate the number of pregnant women who, during pregnancy, have low levels of the vitamin biotin. The hypothesis of this study is that a large number of pregnant women will have low biotin levels. This information will be used to later determine if low biotin levels during pregnancy cause certain birth defects.
Detailed Summary:
Sponsor: University of Arkansas
Current Primary Outcome: Lymphocyte propionyl-CoA carboxylase (PCC) activities [ Time Frame: 2-3 months ]
Original Primary Outcome: Lymphocyte PCC activities [ Time Frame: at start and end of intervention phase ]
Current Secondary Outcome:
- Urinary biotin excretion [ Time Frame: 2-3 months ]
- Urinary 3-hydroxyisovaleric acid (3HIA) excretion [ Time Frame: 2-3 months ]
- Other biotin-related indicators in urine and blood [ Time Frame: 2-3 months ]
Original Secondary Outcome:
- Urinary biotin excretion [ Time Frame: at start and end of intervention phase ]
- Urinary 3HIA excretion [ Time Frame: at start and end of intervention phase ]
Information By: University of Arkansas
Dates:
Date Received: May 6, 2009
Date Started: August 2009
Date Completion:
Last Updated: February 26, 2015
Last Verified: February 2015