Clinical Trial: Pilot Study of Duloxetine in Adult Attention Deficit Hyperactivity Disorder(ADHD)

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Pilot Study of the Efficacy of Duloxetine in Treating Adults With Attention Deficit Hyperactivity Disorder: a Randomized, Controlled Trial.

Brief Summary: The purpose of this study is to determine whether duloxetine is an effective treatment of attention deficit disorder in adults.

Detailed Summary:
Sponsor: Université de Montréal

Current Primary Outcome: Impact of duloxetine on the Conners' Adult attention-Deficit/Hyperactivity Disorder Rating Scale-Observer Report:Screening Version (CAARS-O:SV) in adult ADHD subjects. [ Time Frame: baseline and week 6 ]

Original Primary Outcome: Impact of duloxetine on the Conners' Adult attention-Deficit/Hyperactivity Disorder Rating Scale-Observer Report:Screening Version (CAARS-O:SV) in adult ADHD subjects. [ Time Frame: baseline and weeks 1, 2, 4 and 6 ]

Current Secondary Outcome:

  • Impact of duloxetine on the Clinical Global Impression Scale in ADHD adults [ Time Frame: baseline and week 6 ]
  • Impact of duloxetine on the Conners' Adult attention-Deficit/Hyperactivity Disorder Rating Scale-Self Report : Long Version(44) (CAARS-S:L), in adult ADHD subjects. [ Time Frame: baseline and week 6 ]
  • Impact of duloxetine on anxious and depressive symptoms in adult ADHD subjects. [ Time Frame: baseline and week 6 ]
  • Impact of duloxetine on Quality of life in adults with ADHD [ Time Frame: baseline and week 6 ]
  • Impact of duloxetine on executive functions and cognitive performances in adults with ADHD [ Time Frame: baseline and week 6 ]


Original Secondary Outcome:

  • Impact of duloxetine on the Clinical Global Impression Scale in ADHD adults [ Time Frame: baseline and weeks 1, 2, 4 and 6 ]
  • Impact of duloxetine on the Conners' Adult attention-Deficit/Hyperactivity Disorder Rating Scale-Self Report : Long Version(44) (CAARS-S:L), in adult ADHD subjects. [ Time Frame: baseline and week 6 ]
  • Impact of duloxetine on anxious and depressive symptoms in adult ADHD subjects. [ Time Frame: baseline and week 6 ]
  • Impact of duloxetine on Quality of life in adults with ADHD [ Time Frame: baseline and week 6 ]
  • Impact of duloxetine on executive functions and cognitive performances in adults with ADHD [ Time Frame: baseline and week 6 ]


Information By: Université de Montréal

Dates:
Date Received: July 15, 2009
Date Started: August 2009
Date Completion:
Last Updated: December 13, 2010
Last Verified: December 2010