Clinical Trial: Evaluation of the Role of Plasma Procalcitonin in Prediction of Intra-amniotic Infection in Preterm Premature Rupture of Membrane

Study Status: Completed
Recruit Status: Unknown status
Study Type: Observational

Official Title: Procalcitonin Has a Role to Play in Prediction of Intra-amniotic Subclinical Infection.

Brief Summary: It is hypothesized that the procalcitonin has a role to play in prediction of intra-amniotic subclinical infection.

Detailed Summary:

Study population

  • This study will be conducted at the department of Obstetrics and Gynecology recruiting pregnant women selected from the attendees of antenatal clinic, emergency department and from inpatient wards of Ain Shams University Maternity Hospital from Mars2014.
  • This study will include 100 pregnant women these cases will be divided into 2 groups:
  • Group 1: Healthy preterm Group: will include 50 pregnant females all at 24-34 weeks of gestational age .
  • Group 2: Preterm premature rupture of membrane Group: will include 50 pregnant females all at 24-34 weeks of gestational age

Sponsor: Ain Shams Maternity Hospital

Current Primary Outcome: The correlation between procalcitonin level in PPROM and C-reactive protein level in neonates. [ Time Frame: one year ]

The correlation between procalcitonin level in PPROM and C-reactive protein level in neonates


Original Primary Outcome: Same as current

Current Secondary Outcome: Procalcitonin. - C-reactive protein. - White blood cells count (total and diffrantiated). -C-reactive protein in neonates of groub 2. [ Time Frame: one year ]

Procalcitonin.

  • C-reactive protein.
  • White blood cells count (total and diffrantiated).
  • C-reactive protein in neonates of groub 2.


Original Secondary Outcome: Same as current

Information By: Ain Shams Maternity Hospital

Dates:
Date Received: April 2, 2014
Date Started: May 2014
Date Completion:
Last Updated: April 3, 2014
Last Verified: April 2014