Clinical Trial: Magnesium Sulphate in Perinatal Asphyxia

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Magnesium Sulphate in Perinatal Asphyxia: A Randomized Placebo Controlled Trial.

Brief Summary: Magnesium sulphate has been shown to be neuroprotective. The investigators hypothesize that magnesium sulphate infusion given to babies with perinatal asphyxia should improve outcome in the immediate neonatal period.

Detailed Summary: Magnesium sulphate has a neuroprotective potential as has been shown by many studied in pregnant ladies with eclampsia where it helped neonates also and in mothers with preterm labour where the incidence of cerebral palsy was less. We designed a randomised controlled trial on 40 neonates with severe perinatal asphyxia to see whether it helps in the short term outcome of these neonates.
Sponsor: Sheri Kashmir Institute of Medical Sciences

Current Primary Outcome: good short term out come [ Time Frame: at discharge ]

Original Primary Outcome: good short term out come [ Time Frame: at discharge ]

Current Secondary Outcome: abnormal neurological examination and abnormal CT Head [ Time Frame: at discharge ]

Original Secondary Outcome: Same as current

Information By: Sheri Kashmir Institute of Medical Sciences

Dates:
Date Received: November 2, 2007
Date Started: September 2004
Date Completion:
Last Updated: October 12, 2016
Last Verified: November 2013