Clinical Trial: Dual Hemisphere rTMS for Rehabilitation of Post Stroke Aphasia

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Treatment of Aphasic Stroke Patients With rTMS

Brief Summary: To investigate the therapeutic effect of dual hemisphere repetitive transcranial magnetic stimulation (rTMS) on post-stroke non fluent aphasia.

Detailed Summary: Thirty patients with subacute post-stroke non-fluent aphasia were randomly allocated with a ratio 2:1 to receive real (n = 20) or sham (n = 10) rTMS of the affected motor cortex. Each patient received 1000 rTMS pulses (1 Hertz at 110% of resting motor threshold) over the unaffected Broca's area and 1000 pulses (20 Hertz at 100% resting motor threshold) over affected left Broca's area for 10 consecutive days. LANGUAGE section of hemispheric stroke scale, Stroke Aphasic Depression Questionnaire Hospital Version (SADQ-H) and NIH stroke scale were assessed before, post sessions, 1 and 2 months after the last session . Motor threshold was assessed before and after the end of last session.
Sponsor: Assiut University

Current Primary Outcome: Hemispheric stroke scale (HSS) [ Time Frame: Change from Baseline in HSS at 2 months ]

Language assessment using hemispheric stroke scale (HSS)


Original Primary Outcome: Same as current

Current Secondary Outcome: NIH Stroke Scale (NIHSS) [ Time Frame: Change from Baseline in NIHSS at 2 months ]

Original Secondary Outcome: Same as current

Information By: Assiut University

Dates:
Date Received: March 12, 2013
Date Started: December 2010
Date Completion:
Last Updated: May 8, 2013
Last Verified: May 2013