Clinical Trial: Efficacity of Cognitive Remediation Treatment Compared to a Controlled Group in Young Patient With Anorexia Nervosa

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Prospective Evaluation of Neuropsychological and Clinical Impact of Cognitive Remediation Program Among Children and Adolescents Treated for Anorexia Nervosa

Brief Summary: The aim of research is to test in a randomized clinical trial with active sessions, the efficacy of cognitive remediation therapy in children anorexia nervosa compared to a controlled group. The investigators want to confirm the efficacy of cognitive remediation treatment in children's flexibility problems.

Detailed Summary:

In this research, the investigators want to evaluate remediation cognitive therapy in anorexia nervosa compared to a controlled group (relaxation) based on different factors that testified the cognitive improvement of patients: one week after therapy, six months after and one year after.

Those factors are:

Weight, perfectionism and food symptomatology, temperament, therapeutic alliance and change motivation, clinical evolution of anorexia nervosa, self esteem, executive functions, neuropsychological performance (flexibility and central coherence).


Sponsor: Assistance Publique - Hôpitaux de Paris

Current Primary Outcome: cognitive flexibility [ Time Frame: 6 months after therapy ]

behavioral characteristics related to cognitive difficulties flexibility of anorexic patients, as measured in the medium term (6 months post treatment) by the score of the subscale "shift" BRIEF parent version of the scale (BRIEF-PR).


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Weight status [ Time Frame: 6 months and one year ]
    Assess the impact of cognitive remediation therapy on :Weight status by the Body Mass Index
  • Food symptoms and perfectionism [ Time Frame: 6 months and one year ]
    Assess the impact of cognitive remediation therapy on :Food symptoms and perfectionism measured by the Eating Disorders Inventory auto questionnaire, EDI-2
  • Temperamental profile [ Time Frame: 6 months after therapy ]
    Assess the impact of cognitive remediation therapy on :Temperamental profile measured by the Junior Temperament and Character Inventory questionnaire
  • Therapeutic alliance and motivation to change [ Time Frame: 6 months and one year ]
    Assess the impact of cognitive remediation therapy on : therapeutic alliance and motivation to change measured by self-reported scales Helping Alliance Questionnaire-11 and MOTIV
  • Self-esteem [ Time Frame: 6 months and one year ]
    measured by the Rosenberg Self-Esteem Scale
  • Executive functions [ Time Frame: 6 months and one year ]
    measured by the scale BRIEF-Parent Report
  • Neuropsychological performance in particular flexibility and central coherence [ Time Frame: 6 months and one year ]
    measured by tests of WCST (Wisconsin Card Sorting Test), Geft (Group Embedded Figure Test) and tests the battery Ravello Profile (Tower, Verbal Fluency Test VFT, Trail Making Test TMT, Rey Complex Figure Test Osterreich ROCFT )


Original Secondary Outcome: Same as current

Information By: Assistance Publique - Hôpitaux de Paris

Dates:
Date Received: January 27, 2015
Date Started: March 2015
Date Completion: March 2018
Last Updated: August 12, 2016
Last Verified: August 2016