Clinical Trial: The Effect of CBT- Based Weight Loss Program on Eating Behavior, Weight Loss Result and Risk for Coronary Heart Diseases and Type 2 Diabetes

Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Interventional

Official Title:

Brief Summary: The investigators purpose is to study how CBT (cognitive behavioral therapy)-based weight loss program affects on eating behavior, weight loss and risk factors for CHD (coronary heart diseases)and type 2 diabetes. Moreover, the investigators aim is to recognize subjects suffering from anhedonia (one of the core symptoms of depression, lack of pleasure) and follow how they benefit from the program in order to achieve maintained weight loss. Also, the associations between weight loss, physical activity and musculoskeletal disorders are studied.

Detailed Summary:

Obesity is an increasing problem and effective weight loss methods are needed. The study is randomized follow-up study with 9 months intervention and three (3) years follow-up period. The study is organized in Oulu University Hospital, Department of Internal Medicine. Eighty (80)obese, 20-65 years, study subjects will be randomized into intervention or control group.

The hypothesis of the CognObe study is: CBT (cognitive behavioral therapy)-based weight loss program is successful in sustained and favourable change in eating behavior and weight as well as decreased risk for coronary heart diseases or type 2 diabetes.


Sponsor: University of Oulu

Current Primary Outcome: change in weight [ Time Frame: baseline, 9 months, 1,2 and 3 years ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

  • change in eating behavior [ Time Frame: baseline, 9 months, 1,2 and 3 years ]
    emotional eating, uncontrolled eating, cognitive restraint, binge eating symptoms
  • change in total cholesterol,HDL, LDL,Trigly and glucose [ Time Frame: baseline, 1,2 and 3 years ]
  • DNA [ Time Frame: baseline ]
    for genetic analyses
  • change in incretins [ Time Frame: baseline, 12, 24 and 36 months ]


Original Secondary Outcome: Same as current

Information By: University of Oulu

Dates:
Date Received: May 21, 2012
Date Started: May 2012
Date Completion:
Last Updated: May 23, 2012
Last Verified: May 2012