Clinical Trial: Effect of Ageing on Airway Remodeling

Study Status: Terminated
Recruit Status: Terminated
Study Type: Interventional

Official Title: Study of Bronchoalveolar Lung Remodeling in Subjects From 60 Years Free of Progressive Lung Disease: Structure-function Analysis

Brief Summary: The aim of the study is to investigate the relationship between aging and morphological changes in the lung. 120 consecutive healthy volunteers over 60 years will be enrolled for this trial.

Detailed Summary: Chest multidetector CT without injection and spirometry data will be obtained from a multicentric sample of individuals between 60 and 95 years of ageExclusion criteria were current smoking, history of smoking within the past 10 years, any known chronic or acute pulmonary disease. Individuals treated with Amiodarone, Bleomycin or methotrexate were excludedOutcome
Sponsor: University Hospital, Montpellier

Current Primary Outcome: Bronchial wall thickness [ Time Frame: 1 day ]

Bronchial wall thickness and remodeling associated with aging


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: University Hospital, Montpellier

Dates:
Date Received: August 4, 2010
Date Started: July 2009
Date Completion:
Last Updated: April 14, 2014
Last Verified: April 2014