Clinical Trial: Effect of Intraoperative Nefopam on Acute Pain After Remifentanil Based Anesthesia

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title:

Brief Summary: Many anesthesiologists use the Remifentanil for reducing a surgical pain and stabilizing a vital sign. However, this drug induce postoperative hyperalgesia. Nowadays, many studies report that low-dose Ketamine prevents the opioid-induces hyperalgesia. Nefopam,which is non-opioid analgesic, has similar mechanism with Ketamine. It will be helpful for postoperative pain control, and reduce the needs of opioid.

Detailed Summary:
Sponsor: Hallym University Kangnam Sacred Heart Hospital

Current Primary Outcome:

  • analgesic requirement [ Time Frame: During 1 hour at PACU ]
  • duration of analgesic free [ Time Frame: During 1 hour at PACU ]


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • analgesic requirement [ Time Frame: During 8 hours after arriving at ward ]
  • Pain on the VAS scale [ Time Frame: During 1 hour at PACU ]


Original Secondary Outcome: Same as current

Information By: Hallym University Kangnam Sacred Heart Hospital

Dates:
Date Received: July 2, 2015
Date Started: March 2015
Date Completion:
Last Updated: August 31, 2015
Last Verified: August 2015