Clinical Trial: Comparison of Corticosteroid Dosing Regimens After Endothelial Keratoplasty
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Prospective, Randomized Comparison of Corticosteroid Dosing Regimens Following Endothelial Keratoplasty
Brief Summary: Graft rejection has traditionally been one of the leading causes of cornea transplant failure. To help prevent rejection, corticosteroid eye drops are used for an extended period after transplant surgery. The purpose of this study is to compare the efficacy and side effects of different corticosteroid dosing regimens after endothelial keratoplasty (cornea transplant) surgery.
Detailed Summary:
Sponsor: Cornea Research Foundation of America
Current Primary Outcome: Intraocular Pressure [ Time Frame: from 1 to 12 months after transplant ]
Original Primary Outcome: Change from baseline intraocular pressure [ Time Frame: 1, 3, 6 and 12 months after transplant ]
Current Secondary Outcome: Immunologic Graft Rejection Episode [ Time Frame: within first year after cornea transplantation ]
Original Secondary Outcome: Immunologic Graft Rejection Episode [ Time Frame: within first year after cornea transplantation ]
Information By: Cornea Research Foundation of America
Dates:
Date Received: May 8, 2013
Date Started: March 2013
Date Completion:
Last Updated: April 29, 2015
Last Verified: April 2015