Clinical Trial: Rumination-focused CBT Training for the Prevention of Depression and Anxiety

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Randomized Controlled Trial Evaluating Two Versions of a Rumination-focused CBT Training for the Presence of Depression and Anxiety in Adolescents and Young Adults

Brief Summary: Depression and anxiety disorders are highly prevalent and associated with reduced quality of life for patients and enormous economic costs for society. Although effective treatments are available, a substantial number of patients fail to respond, and the time between disorder onset and treatment is typically long. The development of prevention programs therefore appears promising. The current project aims to prevent depression and anxiety by targeting excessive levels of worry and rumination, two important risk factors for emotional disorders. Participants will be selected on the basis of a high score on two validated questionnaires on worry and rumination. They will be randomly assigned to a rumination-focused cognitive-behavioral training delivered in a group format, a rumination-focused cognitive-behavioral training delivered via internet, or a no-training control condition. It is expected that both versions of the rumination-focused training will reduce symptoms of depression and anxiety, will reduce the incidence of major depressive episodes and generalized anxiety disorder, and will reduce symptom levels of other emotional disorders.

Detailed Summary: see above
Sponsor: VU University of Amsterdam

Current Primary Outcome: Beck Depression Inventory II (BDI-II) [ Time Frame: 1 year after training has ended ]

self-report questionnaire of depressive symptom severity


Original Primary Outcome: Same as current

Current Secondary Outcome: Mood and Anxiety Symptom Questionnaire (MASQ-30) [ Time Frame: 1 year after training has ended ]

Symptom severity of anxiety


Original Secondary Outcome: Same as current

Information By: VU University of Amsterdam

Dates:
Date Received: October 12, 2010
Date Started: October 2010
Date Completion:
Last Updated: December 1, 2014
Last Verified: December 2014