Clinical Trial: Efficacy Study of Cognitive Intervention in Amnestic Mild Cognitive Impairment
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: A Multicenter, Randomized Trial to Assess Efficacy of Home-based and Group Cognitive Intervention Programs in Amnestic Mild Cognitive Impairment
Brief Summary:
- There will be a significant difference in cognitive function between cognitive intervention group (group therapy) and a wait list control group.
- There will be a significant difference in cognitive function between a home-based cognitive intervention group and a wait list control group.
Detailed Summary: The change of Modified ADAS-cog score from the baseline to post-intervention will be compared between the cognitive intervention group and wait list control group.
Sponsor: Inha University Hospital
Current Primary Outcome: Modified Alzheimer's Disease Assessment Scale-Cognitive subscale(ADAS-cog) [ Time Frame: postintervention, 12 weeks follow-up, and 24 weeks follow-up ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- story recall test [ Time Frame: postintervention, 12 weeks follow-up, and 24 weeks follow-up ]
- Digit span forward and backward [ Time Frame: postintervention, 12 weeks follow-up, and 24 weeks follow-up ]
- Word fluency test [ Time Frame: postintervention, 12 weeks follow-up, and 24 weeks follow-up ]
- color-word stroop test [ Time Frame: postintervention, 12 weeks follow-up, and 24 weeks follow-up ]
- Digit symbol test [ Time Frame: postintervention, 12 weeks follow-up, and 24 weeks follow-up ]
- prospective memory test [ Time Frame: postintervention, 12 weeks follow-up, and 24 weeks follow-up ]
- Mini-Mental State Examination [ Time Frame: postintervention, 12 weeks follow-up, and 24 weeks follow-up ]
- CDR-SB [ Time Frame: postintervention, 12 weeks follow-up, and 24 weeks follow-up ]
- K-AD8 [ Time Frame: postintervention, 12 weeks follow-up, and 24 weeks follow-up ]
- PRMQ [ Time Frame: postintervention, 12 weeks follow-up, and 24 weeks follow-up ]
- MMQ-Strategy [ Time Frame: postintervention, 12 weeks follow-up, and 24 weeks follow-up ]
- QOL-AD [ Time Frame: postintervention, 12 weeks follow-up, and 24 weeks follow-up ]
- Geriatric Depression Scale-short form [ Time Frame: postintervention, 12 weeks follow-up, and 24 weeks follow-up ]
- Bayer ADL [ Time Frame: postintervention, 12 weeks follow-up, and 24 weeks follow-up ]
- CGA-NPI [ Time Frame: postintervention, 12 weeks follow-up, and 24 weeks follow-up ]
- Subjective cognitive assessment [ Time Frame: postintervention, 12 weeks follow-up, and 24 weeks follow-up ]
Original Secondary Outcome: Same as current
Information By: Inha University Hospital
Dates:
Date Received: May 20, 2011
Date Started: March 2011
Date Completion:
Last Updated: August 27, 2013
Last Verified: August 2013