Clinical Trial: Measurement of High Order Aberrations in Late Stages Keratoconus

Study Status: Terminated
Recruit Status: Terminated
Study Type: Interventional

Official Title: Feasibility of Measurement of High Order Aberrations in Late Stages Keratoconus by Using an Adaptive Optics Visual Simulator AOVIS-I

Brief Summary: The instrument that will be used in the study is the Murcia monocular Adaptive Optics Visual simulator (AOVIS-I). The system provides an objective characterization of the optical quality of the patient's eye by application of wave-front sensing technology. The optical condition of every eye is represented by its wave aberration. This characterization overcomes the current description based only in refractive errors. This provides an accurate description of the optics of the eye based on the assessment of the whole set of ocular aberrations. The particular wave-front sensor is of a Hartmann-Shack type. One characteristics of this wave-front sensor is its high dynamic range allowing measuring highly aberrated eyes, such as patients with keratoconus.

Detailed Summary: The complete procedure in one patient takes less than 5 minutes and is completely non-invasive.
Sponsor: University Hospital, Toulouse

Current Primary Outcome: The primary outcome of the study is to evaluate the AOVIS-I and its wave-front sensor with high dynamic range for measuring high-order aberrations in patients with late stages (3 and 4) of keratoconus [ Time Frame: at the 1st day ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

  • To evaluate the reliability of the measures in early stages (1 and 2) of keratoconus as compared with a "classic aberrometer". [ Time Frame: at the 1st day ]
  • To describe the measures obtained in advanced stages (3 and 4) of keratoconus. [ Time Frame: at the 1st day ]


Original Secondary Outcome: Same as current

Information By: University Hospital, Toulouse

Dates:
Date Received: February 9, 2011
Date Started: October 2011
Date Completion:
Last Updated: March 1, 2017
Last Verified: March 2017