Clinical Trial: Conventional Collagen Crosslinking in Young Keratoconus

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Evaluation of Conventional Collagen Crosslinking in Young Keratoconus.

Brief Summary:

Keratoconus is a chronic progressive non - inflammatory disorder characterised by progressive steepening and thinning of cornea and high myopic astigmatism, accounting for poor visual acuity in such individuals. Keratoconus seems to be more advanced on presentation, in young patients.

The investigators intend to evaluate the effectiveness of conventional collagen cross linking in young patients diagnosed with keratoconus.


Detailed Summary:

Keratoconus is progressive ectatic corneal disorder characterised by progressive corneal thinning, steep corneal curvatures and usually associated with high irregular myopic astigmatism.

The major problems concerning keratoconus in young patients are;

  1. Rapid rates of progression in young keratoconic corneas as compared to adults.
  2. Poor biomechanical properties of young corneas.
  3. Poor quality of vision, which predisposes to a very poor quality of life.
  4. High rates of complications and failure post keratoplasty in young patients.

The investigators intend to evaluate the effectiveness of conventional collagen crosslinking in young patients with keratoconus with regards to keratometric indices and visual acuity.


Sponsor: Vasan Eye Care Hospital

Current Primary Outcome: Change in Keratometric indices [ Time Frame: 1 months ]

The keratometric readings in the steepest and flattest meridians, along with the average K readings were compared pre and post treatment using conventional collagen cross linking technique at 1 month post cross linking.


Original Primary Outcome: Same as current

Current Secondary Outcome: Improvement in vision [ Time Frame: 12 months ]

Comparison of visual rehabilitation was done as improvements noted in Snellen line numbers and best corrected visual acuity (B.C.V.A) converted to decimals, pre and post treatment at 1,3,6,12 months post treatment.


Original Secondary Outcome: Same as current

Information By: Vasan Eye Care Hospital

Dates:
Date Received: December 2, 2013
Date Started: January 2012
Date Completion:
Last Updated: December 12, 2013
Last Verified: December 2013