Clinical Trial: Characterization of Local and Systemic Bone Markers in Diabetes Patients With Charcot Osteoarthropathy
Study Status: Enrolling by invitation
Recruit Status: Enrolling by invitation
Study Type: Observational
Official Title:
Brief Summary:
The study is designed to investigate biomarkers related to bone turnover in diabetics with charcot foot. This is done by measuring local blood samples in the feet, and systemically in a vene and an artery. Measurements are done before and after cooling the feet in icewater to lower the bloodflow.
Patients will be compared with healthy diabetic controls.
Detailed Summary:
Sponsor: Bispebjerg Hospital
Current Primary Outcome: RANKL [ Time Frame: 10 min between measurements ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- osteocalcin [ Time Frame: 10 min between measurements ]
- CTX-I [ Time Frame: 10 min between measurements ]
- sRAGE [ Time Frame: 10 min between measurements ]
- P1NP [ Time Frame: 10 min between measurements ]
Original Secondary Outcome: Same as current
Information By: Bispebjerg Hospital
Dates:
Date Received: February 27, 2015
Date Started: February 2015
Date Completion:
Last Updated: March 6, 2015
Last Verified: March 2015