Clinical Trial: Physical Activity to Reduce Joint Pain During Aromatase Inhibitor Therapy

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Physical Activity to Reduce Joint Pain During Aromatase Inhibitor Therapy

Brief Summary: For post-menopausal women diagnosed with hormone-receptor positive breast cancer tumors, aromatase inhibitors (AIs) are the standard adjuvant hormone treatment to prolong disease-free survival and time-to-recurrence. Unfortunately, joint pain/stiffness/achiness (arthralgia) is a common side-effect of AIs. This "proof-of-concept" study explores how an evidence-based physical activity (PA) program- the Arthritis Foundation's Walk with Ease (WWE) program- can be adapted for breast cancer survivors on AI therapy to: 1) Help them maintain or achieve recommended levels of PA, 2) reduce their joint pain/stiffness/achiness, and 3) thereby enable them to remain on AI therapy as prescribed.

Detailed Summary:
Sponsor: University of North Carolina, Chapel Hill

Current Primary Outcome: Self-reported joint pain [ Time Frame: 6 weeks ]

A valid and reliable 10cm Visual Analog Scale will be used to assess self-reported joint pain. This scale has been used in numerous trials.


Original Primary Outcome: Same as current

Current Secondary Outcome: Self-reported walking [ Time Frame: 6 weeks ]

This will be measured by the number of days walked per week and the number of minutes per walk.


Original Secondary Outcome: Same as current

Information By: University of North Carolina, Chapel Hill

Dates:
Date Received: July 11, 2013
Date Started: August 2013
Date Completion:
Last Updated: August 5, 2016
Last Verified: August 2016