Clinical Trial: Ropivacaine Volume for Ultrasound-guided Retrograde Infraclavicular Brachial Plexus Block

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Ropivacaine Volume for Ultrasound-guided Retrograde Infraclavicular Brachial Plexus Block

Brief Summary: The retrograde infraclavicular brachial plexus block has been proved an effective and safe approach. Realtime ultrasound guide will facilitate a successful peripheral nerve block. The purpose of this study was to determine the medium effective volume required to produce an effective retrograde infraclavicular block using an ultrasound (US)-guided technique.

Detailed Summary: Thirty adults undergoing elective upper limb surgery received an US-guided retrograde infraclavicular block. The initial concentration of 0.5% ropivacaine injected was 30 ml, which was subsequently varied at a ratio of 1: 1.2 for each consecutive patient according to the response of the previous patient. The medium effective volume (EV50) was determined using the Dixon and Massey up-and-down method. The effective volume in 95% of patients (EV95) was calculated using probit regression.
Sponsor: Beijing Jishuitan Hospital

Current Primary Outcome: VAS of brachial plexus innervated area [ Time Frame: 20 minutes ]

effect and side effects of the present block approach for brachial plexus.


Original Primary Outcome: Same as current

Current Secondary Outcome: medium effective ropivacaine volume [ Time Frame: about 2 months ]

The initial concentration of 0.5% ropivacaine injected was 30 ml, which was subsequently varied at a ratio of 1: 1.2 for each consecutive patient according to the response of the previous patient. The medium effective volume (EV50) was determined using the Dixon and Massey up-and-down method. EV95 was calculated using probit regression.


Original Secondary Outcome: Same as current

Information By: Beijing Jishuitan Hospital

Dates:
Date Received: April 7, 2011
Date Started: March 2010
Date Completion:
Last Updated: April 12, 2011
Last Verified: February 2010