Clinical Trial: Hookworm Immune Regulation Project
Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Interventional
Official Title: Study of Immuno-regulatory Mechanisms Induced by Hookworm Infection
Brief Summary: The main objective of this study is to characterize the regulatory immune response induced by hookworm in an infected Vietnamese rural population from the periphery of HCM, evolution after infection treatment and during potential naturally reinfection.
Detailed Summary:
Population: 20 healthy adults (18-65 years) infected and non infected by Hookworm will be recruited and treated according to Good Clinical Practice recommendations.
Allergy will be excluded by skin prick tests. Amount and phenotype of Treg will be explored at several time points. Subsequent culture with environmental antigen will be performed on cryopreserved cells.
Sponsor: Brugmann University Hospital
Current Primary Outcome: Amount and phenotype of Treg [ Time Frame: 0-12 weeks ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Brugmann University Hospital
Dates:
Date Received: September 16, 2014
Date Started: August 2014
Date Completion: March 2017
Last Updated: July 25, 2016
Last Verified: July 2016