Clinical Trial: Alpers Huttenlocher Natural History Study

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Natural History Study of Alpers Huttenlocher Syndrome

Brief Summary: This is a natural history study of Alpers Huttenlocher Syndrome. Patients will be followed over time to assess clinical symptoms for the purpose of expanding knowledge of this disorder in the medical community.

Detailed Summary: The study team will conduct outpatient visits to the medical center on a 6 month basis, or as patients are able. The patients or their caregivers will complete medical and symptom questionnaires.
Sponsor: Columbia University

Current Primary Outcome: onset age [ Time Frame: 2 years ]

age at onset of first symptom versus POLG mutation type


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Columbia University

Dates:
Date Received: January 25, 2017
Date Started: January 2014
Date Completion: December 2020
Last Updated: January 25, 2017
Last Verified: January 2017