Clinical Trial: Laparoscopic Adrenalectomy Versus Radiofrequency Ablation
Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Interventional
Official Title: Laparoscopic Adrenalectomy Versus Radiofrequency Ablation for Aldosterone-producing Adenoma: a Prospective Randomized Controlled Trial
Brief Summary:
This is a prospective randomized controlled study comparing laparoscopic adrenalectomy (LA) versus image-guided percutaneous radiofrequency ablation (RFA) in treating aldosterone-producing adenoma.
The objectives of this study are to
- compare the short-term outcomes of LA and RFA in treating aldosterone-producing adenoma.
- compare the treatment success rates of LA and RFA during follow-up for primary aldosteronism.
Detailed Summary:
Sponsor: Chinese University of Hong Kong
Current Primary Outcome:
- Morbidity rate [ Time Frame: 30-day ]
- Resolution of hyperaldosteronism [ Time Frame: 1 year ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Operative time [ Time Frame: 24 hours ]
- Periprocedural hypertensive crisis [ Time Frame: 24 hours ]
- Mortality rate [ Time Frame: 30 days ]
- Blood loss [ Time Frame: 24 hours ]
- Analgesic requirement [ Time Frame: 30 days ]
- Time to resumption of activity [ Time Frame: 30 days ]
- Resolution of hypokalaemia [ Time Frame: 1 year ]
- Blood pressure control [ Time Frame: 1 year ]
- Hospital stay [ Time Frame: 30 days ]
- Pain score [ Time Frame: 7 days ]
Original Secondary Outcome: Same as current
Information By: Chinese University of Hong Kong
Dates:
Date Received: January 5, 2014
Date Started: January 2013
Date Completion: December 2017
Last Updated: April 22, 2017
Last Verified: April 2017
