Clinical Trial: Effects of Zeolite + Dolomite on Performance and Acidosis

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Effects of Dietary Zeolite + Dolomite on Performance, Exercise-induced Acidosis, Oxidative Stress, Inflammation and Intestinal Barrier Dysfunction in Trained People

Brief Summary:

Purpose:

This study investigates the effects of dietary zeolite + dolomite on performance, exercise-induced acidosis, oxidative stress, inflammation and intestinal barrier dysfunction in trained people.

Hypotheses (H1):

Zeolite + dolomite increase performance in an ergometer step test Zeolite + dolomite reduce exercise-induced acidosis Zeolite + dolomite reduce oxidative stress Zeolite + dolomite reduce inflammation Zeolite + dolomite improve intestinal barrier dysfunction


Detailed Summary:

The application of adequate nutraceuticals for sporty people´s performance and health becomes more and more interesting for athletes and their carers. There are also great opportunities for product providers in this field to act commercially profitable.

Beside the main goal - to achieve improved performance - modern sport nutraceuticals should support immunity of athletes in all corners of health. One of the most interesting approaches in this field is to promote performance and health via dietary zeolites. Zeolites are synthetic microporous crystals containing AIO4 and SiO4 tetrahedrons. It is hypothesized that in human body these silicates act as gut-located adsorbents of chymus molecules or as ion-exchangers, catalysts, detergent builders or antidiarrheic agents (1, 2, 3, 4). These - mainly physical - effects of dietary used zeolite might also influence the chief issues of modern sport nutrition: performance, acidosis, oxidative stress, inflammation, gastrointestinal complaints and associated impacts on immunity and health.

The investigators hypothesize that the physical effects of zeolite affect the metabolism in the gut and exert systemic physiological/biochemical benefits in regard to human´s exercise performance, redox biology, inflammatory processes, acid-base balance, and even intestinal barrier integrity/function. All these postulated benefits would have tremendous impact on sports performance. However, up to date no clinical study is reported on PubMed that addresses these chief aims of sport nutrition in the context of zeolite supplementation.

GOALS

This protocol describes a study that investigates the effects of dietary zeolite + dolomite (Product name: "PANACEO SPORT") on performance, exerci
Sponsor: Green Beat

Current Primary Outcome: Change of aerobic performance capability between baseline, 4 and 12 weeks [ Time Frame: 0, 4, 12 weeks ]

Zeolite and Dolomite might influence maximum aerobic performance due to attenuated lactate accumulation in a step test ergometry


Original Primary Outcome: Change of aerobic performance capability and maximum oxygen uptakte between baseline, 4 and 12 weeks [ Time Frame: 0, 4, 12 weeks ]

Zeolithe and Dolomite might influence maximum aerobic performance due to attenuated lactate accumulation in a step test ergometry


Current Secondary Outcome: Change of lactate concentrations in blood between baseline, 4 and 12 weeks [ Time Frame: 0, 4, 12 weeks ]

Lactate accumulation and -kinetics is influenced by dietary zeolite and dolomite supplementation


Original Secondary Outcome: Change of lactate kinetics and maximum lactate concentrations in blood between baleline, 4 and 12 weeks [ Time Frame: 0, 4, 12 weeks ]

Lactate accumulation and -kinetics is influenced by dietary zeolithe and dolomit supplementation


Information By: Green Beat

Dates:
Date Received: April 9, 2013
Date Started: April 2013
Date Completion:
Last Updated: February 9, 2016
Last Verified: February 2016