Clinical Trial: Effect of Melatonin on Body Composition, Glucose Metabolism and Lipid Metabolism

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Effect of Melatonin on Body Composition, Glucose Metabolism and Lipid Metabolism

Brief Summary: Effect of Melatonin on Body Composition, Glucose Metabolism and Lipid Metabolism.

Detailed Summary: The effect of Melatonin on Body Composition, Glucose Metabolism and Lipid Metabolism in patient with obesity and acanthuses nigrican.
Sponsor: Shanghai 10th People's Hospital

Current Primary Outcome: insulin resistance index [ Time Frame: 12 weeks ]

HOMA-IR:serum fasting insulin(mmol/L) × serum fasting glucose(mmol/L)/22.5


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Blood pressure [ Time Frame: 12 weeks ]
    Systolic blood pressure (mmHg) and diastolic blood pressure (mmHg)
  • Body weight [ Time Frame: 12 weeks ]
    Body weight (kg)
  • Body fat [ Time Frame: 12 weeks ]
    Body fat (%)
  • Neck circumference [ Time Frame: 12 weeks ]
    Neck circumference (cm)
  • Waist circumference [ Time Frame: 12 weeks ]
    Waist circumference (cm)
  • Total Cholesterol [ Time Frame: 12 weeks ]
    Total Cholesterol (mmol/L)
  • Triglyceride [ Time Frame: 12 weeks ]
    Triglyceride (mmol/L)
  • Low Density Lipoprotein [ Time Frame: 12 weeks ]
    Low Density Lipoprotein (mmol/L)
  • High Density Lipoprotein [ Time Frame: 12 weeks ]
    High Density Lipoprotein (mmol/L)


Original Secondary Outcome: Same as current

Information By: Shanghai 10th People's Hospital

Dates:
Date Received: November 5, 2015
Date Started: May 2014
Date Completion:
Last Updated: November 13, 2015
Last Verified: November 2015